• Grape Seed Extract
  • 95% Proanthocyanidin       UV

    Sources of Grape Seed Extract

    Grape seed extracts are industrial derivatives from whole grape seeds that have a great concentration of vitamin E, flavonoids, linoleic acid and phenolic procyanidins (also known as OPC or oligomeric procyanidins). The typical commercial opportunity of extracting grape seed constituents has been for chemicals known as polyphenols having antioxidant activity in vitro.

    Ingredients of Grape Seeds Extract

    95%Proanthocyanidian        UV

    Specification of Grape Seed Extract

    Specification of  grape seed extract
    Botanical Source:  Vitis vinifera L. 
    Part used: seed 
    Specification: 95%Proanthocyanidian      UV
    Appearance  Red brown powder  (Relate to Purity)
      Flavor & Odor Characteristic
      Particle size 100% pass 80 mesh
      Loss on Drying ≤5.0%
    Bulk density 40-60g/100ml
    Sulphated Ash ≤5.0%
    GMO Free
    General Status Non-irradiated
      Pb ≤3mg/kg
      As ≤1mg/kg
      Hg  ≤0.1mg/kg
      Cd  ≤1mg/kg
      Total microbacterial count ≤1000cfu/g
      Yeast & Mold  ≤100cfu/g
      E.Coli Negative 
     Staphylococcus aureus Negative  
      Salmonella  Negative 
    Enterobacteriaceaes Negative

    Study of Grape Seed Extract

    The grape seed extract has been linked to a wide range of possible therapeutic properties including healing wounds and treating conditions such as high cholesterol, atherosclerosis, macular degeneration, poor circulation, nerve damage, as well as preventing cancer.it increasesnatural antioxidant and anti-inflammatory concentrations and may will have a favorable effect on cardiovascular risk factors.

    Reference of Grape Seed Extract

    1、 Gao, N.; Budhraja, A.; Cheng, S.; Yao, H.; Zhang, Z.; Shi, X. (2009). "Induction of Apoptosis in Human Leukemia Cells by Grape Seed Extract Occurs via Activation of c-Jun NH2-Terminal Kinase". Clinical Cancer Research 15 (1): 140–9. doi:10.1158/1078-0432.CCR-08-1447. PMC 2760842.

    2、 Khanna, Savita; Venojarvi, Mika; Roy, Sashwati; Sharma, Nidhi; Trikha, Prashant; Bagchi, Debasis; Bagchi, Manashi; Sen, Chandan K (2002). "Dermal wound healing properties of redox-active grape seed proanthocyanidins". Free Radical Biology and Medicine 33 (8): 1089–96..

    3、 Yahara, N; Tofani, I; Maki, K; Kojima, K; Kojima, Y; Kimura, M (2005). "Mechanical assessment of effects of grape seed proanthocyanidins extract on tibial bone diaphysis in rats". Journal of musculoskeletal & neuronal interactions 5 (2): 162–9.

    4、 Katiyar, Santosh K. (2008). "Grape seed proanthocyanidines and skin cancer prevention: Inhibition of oxidative stress and protection of immune system". Molecular Nutrition & Food Research. 52 Suppl 1: S71–6.

    5、 Su, X; d'Souza, DH (2011). "Grape seed extract for control of human enteric viruses". Applied and environmental microbiology 77 (12): 3982–7.

    6、 Mellen, Philip B.; Daniel, Kurt R.; Brosnihan, K. Bridget; Hansen, Kim J.; Herrington, David M. (2010). "Effect of Muscadine Grape Seed Supplementation on Vascular Function in Subjects with or at Risk for Cardiovascular Disease: A Randomized Crossover Trial". Journal of the American College of Nutrition 29 (5): 469–75.

    7、 Feringa, Harm H.H.; Laskey, Dayne A.; Dickson, Justine E.; Coleman, Craig I. (2011). "The Effect of Grape Seed Extract on Cardiovascular Risk Markers: A Meta-Analysis of Randomized Controlled Trials". Journal of the American Dietetic Association 111 (8): 1173–81.

    8、 Shanmuganayagam, Dhanansayan; Beahm, Mark R.; Osman, Hashim E.; Krueger, Christian G.; Reed, Jess D.; Folts, John D. (2002). "Grape Seed and Grape Skin Extracts Elicit a Greater Antiplatelet Effect When Used in Combination than When Used Individually in Dogs and Humans". The Journal of Nutrition 132 (12): 3592–8.

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