• Polygonum Cuspidatum Extract

  • Description of Polygonum Cuspidatum Extract

    Latin Name: Polygonum Cuspidatum

    Part Used: Root

    10%,20,50%,98% Resveratrol



    Sources of Polygonum Cuspidatum Extract

    Polygonum cuspidatum is the biggest of the three invasive knotweeds, with stems usually between 6 and 16 feet, but reaching as much as 17 feet tall is some areas. The stems are smooth, hollow and light green, resembling the canes of bamboo, and sparingly branched. The leaves are 6 to 16" long, with a deeply heart-shaped base and a blunt leaf tip. Diagnostic hairs on the leaf underside are long, thin and wavy (hairs are sparse and sometimes fall off late in the season, best seen with a hand lens June through midSeptember).The flowers are small, creamy white to greenish white, and grow in short, branched clusters from leaf axils near the ends of the stems. Flower clusters are generally shorter than the subtending leaf, unlike the longer flower clusters found on Japanese knotweed and the mid-size clusters found on the hybrid Bohemian knotweed. Leaf and flower characters are most reliable when looking near the middle of a branch. The fruit is 3-sided, black and shiny.



    Ingredients of Polygonum Cuspidatum Extract

    Formula:C14H12O3

    CAS NO. 501-36-0

    MOLECULAR WEIGHT 228.25

    Resveratrol is a polyphenol compounds, mainly derived from grape (red wine), giant knotweed, peanut, mulberry and other plants. Resveratrol is a kind of biological strong natural polyphenols, also known as the three phenol stilbene, is cancer chemoprevention agents, is also to reduce platelet aggregation, the prevention and treatment of atherosclerosis, disease of heart head blood-vessel chemoprophylaxis agent. The United States department of agriculture research results show that the peanut and ren also contains a considerable amount of resveratrol in red. The resveratrol, experimental studies have confirmed that have beneficial effects on cardiovascular disease and cancer.



    Specification of Polygonum Cuspidatum Extract

    Item

    Specification

    Assay(Resveratrol by HPLC)   NLT 70.0 %
    Emodin NMT6.0%
    Loss on Drying NMT 2.0%
    Ultraviolet light 303nm
    Sieve 95% pass 100 mesh
    Ash NMT 0.5%
    Heavy Metals NMT 20ppm
    Arsenic NMT 1ppm
    Residual Ethyl Acetate NMT 1ppm
    Microbiological control
    Total plate count <1000/ g

    Yeast & mold

    <100/ g

    E.coil

    Negative

    Salmonelia

    Negative



    Study of Polygonum Cuspidatum Extract

    a.Resveratrol can reduce blood viscosity, inhibit platelet coagulation and vasodilation, keep the blood flowing smoothly.

    b.Resveratrol can prevent cancer occurrence and development.

    c.Resveratrol has resistance atherosclerosis and coronary heart disease, ischemic heart disease, hyperlipidemia prevention role.

    d.Resveratrol can be sued as the role of inhibiting tumor also have estrogen-like effect, can be used to treat diseases such as breast cancer.

    e.Resveratrol has anticancer, cardiovascular protection, free-radical, anti-inflammatory and antibacterial effects,ect



    Reference of Polygonum Cuspidatum Extract

    1 Dong-Geng Wang,Wen-Ying Liu,Guang-Tong Chen, A simple method for the isolation and purification of resveratrol from polygonum cuspidatum ,Journal of Pharmaceutical Analysis,3(4).2013:241–247.

    2 Bin Shan,Yi-Zhong Cai,John D. Brooks,Antibacterial properties of polygonum cuspidatum roots and their major bioactive constituents, Food Chemistry,109(3),2008:530-537.

    3 Yingming Pan,Xiaopu Zhang,Hengshan Wang,Antioxidant potential of ethanolic extract of polygonum cuspidatum and application in peanut oil, Food Chemistry,105(4),2007: 1518–1524.

    4 Kai-Jin Wang, Ying-Jun Zhang,Chong-Ren Yang,Antioxidant phenolic compounds from rhizomes of polygonum paleaceum,Journal of Ethnopharmacology,96(3),2005: 483–487

    5 Wei Peng,Rongxin Qin,Xiaoli LiBotany, phytochemistry, pharmacology, and potential application of polygonum cuspidatum Sieb.et Zucc.: A review,Journal of Ethnopharmacology,148,(3) , 2013: 729–745


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