• Red Clover Extract

  • Description of Red Clover Extract

    2.5%-20%Isoflavones by HPLC

    Botanical Source :Trifolium pretense L.

    Part Used: Leave &Flower



    Sources of Red Clover Extract

    Red clover (Trifolium pratense in Latin), which belongs to the family of Leguminosae, is a perennial with trifoliate leaves and pink to red flowers.Red Clover widely distributes in Europe, the British Isles, China and many other countries. It is one of the worlds oldest agricultural crops, widely cultivated as a fodder crop and as a source of hay for cattle and sheep. It has long been used in Western herbal traditions as a blood purifier.



    Ingredients of Red Clover Extract

    Sissotrin, Daidzein, Ononin, Genistein

    Formononetin, Abiochanin A



    Specification of Red Clover Extract

    Item Specification
    Assay Total isoflavone≥20.0%
      Daidzein
      Genistein
      Formononetin
      Biochanin A
    Appearance Fine powder
    Color Brown
    Taste Characteristic
    Odor Characteristic
    Identification Positive
    Sieve   Analysis 100% pass 80 mesh
    Part of Plant   Used Leaves & Flowers
    Ash 5% Max
    Loss on   Drying  5% Max
    Heavy   metals NMT 10ppm
    Arsenic (As) NMT 2ppm
    Cadmium(Cd) NMT 1ppm
    Lead (Pb) NMT 5ppm
    Mercury(Hg) NMT 2ppm
    Total Plate   Count  10000cfu/g Max
    Yeast &   Mold 100cfu/g Max
    E.Coli Negative
    Salmonella Negative



    Study of Red Clover Extract

    Red clover is considered to be one of the richest sources of isoflavones, these isolated isoflavones have the certain benefits, and can be used to treat menopause, hot flushes, cardiovascular health and bone loss. However, an actual protective action in humans remains to be demonstrated. In the meantime, Red clover is valued for its ability to loosen phlegm and calm bronchial spasms.

    1.For women, stimulate eostrogenic activity, increase fertility, and reduce hot flashes experienced by women during menopause

    2.Anti-cancer

    3.One of the most useful remedies for children with skin problems

    4.Expectorant and anti-spasmodic

    5.Relieve the syndrome of irritation and inflammation of urinary tract



    Reference of Red Clover Extract

    1、 Paola Spagnuolo,Emanuela Rasini,Alessandra Luini,Isoflavone content and estrogenic activity of different batches of red clover (Trifolium pratense L.) extracts: An in vitro study in MCF-7 cells,Fitoterapia.94,2014: 62–69.

    2、 L. Krenn,D.H. Paper, Inhibition of angiogenesis and inflammation by an extract of red clover (Trifolium pratense L.), Phytomedicine,16(12),2009: 1083–1088.

    3、 Thanasan Khaosaad,Liselotte Krenn,Svjetlana Medjakovic,Effect of mycorrhization on the isoflavone content and the phytoestrogen activity of red clover, Journal of Plant Physiology,165( 11), 2008:1161–1167.

    4、 Martin Imhof,Anca Gocan,Franz Reithmayr, Effects of a red clover extract (MF11RCE) on endometrium and sex hormones in postmenopausal women, Maturitas,55(1),2006:76–81.

    5、 V. Beck,U. Rohr,A. Jungbauer,Phytoestrogens derived from red clover: An alternative to estrogen replacement therapy ? The Journal of steroid Biochemistry and Molecular Biology,94(5),2005:499-518.

    6、 G.Th. Kroyer,Red clover extract as antioxidant active and functional food ingredient , Innovative Food Science & Emerging Technologies, 5(1),2004:101–105.

    7、 A. Brandli, J.S. Simpson,S. Ventura,Isoflavones isolated from red clover (Trifolium pratense) inhibit smooth muscle contraction of the isolated rat prostate gland,Phytomedicine,17(11),2010: 895–901.

    8、 Akira Mine, Kiwamu Hyodo, Atsushi Takeda, Interactions between p27 and p88 replicase proteins of Red clover necrotic mosaic virus play an essential role in viral RNA replication and suppression of RNA silencing via the 480-kDa viral replicase complex assembly, Virology,107(2),2010: 213–224.

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